Sotorasib (Lumakras,Sotoldx)

Sotorasib covalently binds to the switch pocket of KRAS G12C mutant protein, specifically inhibits GTPase activity and blocks abnormal RAS signaling.

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Sotorasib Drug News

FDA Approves Sotorasib in Combination with Panitumumab for the Treatment of Metastatic Colorectal Cancer with KRAS G12C Mutation

On January 17, 2025, Amgen announced that the U.S. Food and Drug Administration (FDA) has approved Lumakras (sotorasib) in combination with Vectibix (···【More】
Update: 27 Apr,2026Source: BigbearViews: 73
The FDA has approved sotorarazib (Lumakras) in combination with panitumumab

Here is the professional, accurate English translation of the full text, formatted for medical/pharmaceutical documentation:On May 28, 2021, Amgen ann···【More】
Update: 04 Mar,2026Source: BigbearViews: 96
The FDA has approved sotorarazib (Lumakras) in combination with panitumumab

On January 17, 2025, Amgen announced that the U.S. Food and Drug Administration (FDA) has approved the combination of sottorazib (Lumakras) and panitu···【More】
Update: 04 Mar,2026Source: BigbearViews: 96